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17α-Hydroxyprogesterone Pharmacy Steroids CAS 68-96-2 17α-OHP

Categories Raw Steroid Powders
Brand Name: Muscle building
Model Number: 84371-65-3
Certification: HSE, ISO 9001, USP, BP
Place of Origin: China
MOQ: Negotiable
Price: Negotiable
Payment Terms: T/T, Western Union, Money Gram, Bitcoin
Supply Ability: 1000kg/month
Delivery Time: 12 hours within your payment is received
Packaging Details: As you require
Molecular Formula: C21H30O3
Molecular Weight: 330.46
CAS Registry Number: 68-96-2
Assay: 99%
mp: 276°C
refractive index: 90 ° (C=1, CHCl3)
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    17α-Hydroxyprogesterone Pharmacy Steroids CAS 68-96-2 17α-OHP

    17α-Hydroxyprogesterone Pharmacy Steroids CAS 68-96-2 17α-OHP


    Quick Detail

    CAS68-96-2
    MFC21H30O3
    MW33046.00%
    EINECS200-699-4
    Product CategoriesSteroids;Biochemistry;Hydroxyketosteroids;Intermediates & Fine Chemicals;Pharmaceuticals;MIRADON
    mp276°C
    refractive index90 ° (C=1, CHCl3)
    storage temp.-20℃ Freezer
    Chemical PropertiesWhite Solid
    UsageProgesteron. It was isolated from adrenal glands.
    Usageanticoagulant
    Usage17α-Hydroxy Progesterone is a metabolite of Progesterone. It was isolated from adrenal glands.

    Description

    Generic Name: hydroxyprogesterone (hye-DROX-ee-proe-JES-ter-one)
    Brand Name: Makena


    17α-Hydroxyprogesterone (17α-OHP), or hydroxyprogesterone (OHP) (INN, BAN), also known as 17α-hydroxypregn-4-ene-3,20-dione, is an endogenous progestogen steroid hormone related to progesterone. It is also a chemical intermediate in the biosynthesis of many other endogenous steroids, including androgens, estrogens, glucocorticoids, and mineralocorticoids, as well as neurosteroids.


    Under the brand name Gestageno, 17α-OHP has been marketed for clinical use in Argentina. However, esters of 17α-OHP, including hydroxyprogesterone caproate, as well as hydroxyprogesterone acetate and hydroxyprogesterone heptanoate to a much lesser extent, have been used far more widely in comparison, and when "hydroxyprogesterone" is referenced from the standpoint of medical use, what is usually being referred to is actually, in general, hydroxyprogesterone caproate.


    17α-OHP is also the parent compound of a class of progestins referred to as the 17α-hydroxyprogesterone derivatives. Among others, this class of drugs includes chlormadinone acetate, cyproterone acetate, hydroxyprogesterone caproate, medroxyprogesterone acetate, and megestrol acetate.


    17α-OHP is derived from progesterone via 17α-hydroxylase (encoded by CYP17A1), or from 17α-hydroxypregnenolone via 3β-hydroxysteroid dehydrogenase/Δ5-4 isomerase.


    17α-OHP increases in the third trimester of pregnancy primarily due to fetal adrenal production.

    This steroid is primarily produced in the adrenal glands and to some degree in the gonads, specifically the corpus luteum of the ovary. Normal levels are 3-90 ng/dl in children, and in women, 20-100 ng/dl prior to ovulation, and 100-500 ng/dl during the luteal phase.


    Hydroxyprogesterone is used for:
    Reducing the risk of delivering a baby too early (preterm birth). Hydroxyprogesterone should only be used by women who are pregnant with one baby and have had a preterm delivery of one baby in the past.

    Hydroxyprogesterone is a synthetic hormone (progestin). How it works to reduce the risk of recurrent preterm birth is not known.



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